An additional 42 genes connected to the development of Alzheimer's disease have been uncovered in the largest study of genetic risk for Alzheimer's to date.
"This is a landmark study in the field of Alzheimer's research and is the culmination of 30 years' work," study co-author Julie Williams, center director at the UK Dementia Research Institute at Cardiff University,"Lifestyle factors such as smoking, exercise and diet influence our development of Alzheimer's, and acting to address these now is a positive way of reducing risk ourselves," she added.
"The new risk variants identified in the present study are significantly associated with progression" to Alzheimer's disease, says the study, published Monday in theThe discovery will provide scientists with potential new targets for treatments, medications and lifestyle changes that might reduce the risk of the deadly brain disease, experts say.
Of the 42 new genes found to be connected to Alzheimer's, many clustered into several suspected but unconfirmed pathways for disease development. One such pathway is the body's immune system, designed to protect us from germ invaders. One protein that stood out in the study was tumor necrosis factor alpha, which is made by the immune system to regulate inflammation. The study found a cluster of genes associated with TNF, as it is called. Though the chemical's true role is to gather the body's defenses for a fight, it is also a culprit in many autoimmune diseases in which the body turns upon itself, such as rheumatoid and psoriatic arthritis, Crohn's disease and type 1 diabetes.
México Últimas Noticias, México Titulares
Similar News:También puedes leer noticias similares a ésta que hemos recopilado de otras fuentes de noticias.
42 previously unknown genes discovered for Alzheimer's disease in 'landmark study'An additional 42 genes connected to the development of Alzheimer's disease have been uncovered in the largest study of genetic risk for Alzheimer's to date.
Leer más »
42 previously unknown genes discovered for Alzheimer's diseaseA unprecedented global study of Alzheimer's disease has uncovered an additional 42 genes that may affect a person's risk of developing the disorder. Doctors hope to use that information to develop a more precise way to identify risk.
Leer más »
After 42 years and a COVID delay, Dodger Stadium readies for All-Star momentThe Dodgers were supposed to host the 2020 All-Star game, but that was canceled by the pandemic. They'll finally get it after waiting 42 years for another shot.
Leer más »
Podcast: Goodbye, Title 42Title 42 has severely limited asylum cases since the Trump administration put the public health order in place in 2020. Will the Biden administration revocation make it easier for refugees to enter U.S.?
Leer más »
Democrats to Spend $10B on Pandemic Funds While Ending Title 42The Democrats on Monday agreed to spend $10 billion in “emergency” pandemic funding while ending Title 42—which prohibits the entry of immigrants who pose health risks.
Leer más »
All of MLB to wear Jackie Robinson's No. 42 in Dodger Blue on April 15All major league players, managers, coaches and umpires will wear Jackie Robinson's No. 42 in Dodger Blue for the first time on April 15, the 75th anniversary of his breaking the major league color barrier.
Leer más »