The FDA has approved Zurzuvae, the first-ever pill for treating postpartum depression. Here’s how it works.
of postpartum depression are multi-factorial and include everything from genetics and hormonal changes to a strained social support system, pregnancy complications and financial stress. Having a personal or family history of a mental health issue like depression or bipolar disorder can increase a person’s risk, as can having a baby with a health complication, going through with an unwanted pregnancy, experiencing difficulty with breastfeeding, or having problems with a partner.
Zuranolone is a neuroactive steroid that affects the primary neurotransmitter in the brain, binding to receptors and boosting activity that can restore dysregulated networks“That’s the hypothesis of why it could be impacting depression in the perinatal period,” says McMahon.
The women were split up into two groups: 98 took 50 milligrams of zuranolone once daily for 14 days and the other 98 took a placebo. By day 15, 57% of those who took the pill said their depressive symptoms had improved by at least 50%, and 26.9% achieved remission.develop depression during pregnancy or post-delivery.
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