HIV has a high mutation rate, which helps it adapt to evade both natural immune systems and artificial vaccines. Has Moderna created a vaccine which the virus cannot easily dodge?
Undaunted, Moderna, a firm based in Massachusetts that has recently found fame by quickly coming up with a viable covid-19 jab, is planning to start human trials of a novel vaccine againsttechnology used to produce its covid-19 jab will succeed againstModerna’s approach is based in part on work by the InternationalVaccine Initiative , a charity, and Scripps Research, a not-for-profit institute in San Diego.
This is the means by whichparticles “dock” with their target cells prior to infecting them. The part of the protein that does the docking is so well tailored that almost any mutation will make it less effective. Since gp120 is trapped in an evolutionary corner, it is a desirable target for a vaccine.-cells are diverse but rare. Each carries the blueprint of an antibody, and stands ready to do two things when alerted to the presence of a pathogen.
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