An experimental skin patch is showing promise to treat toddlers who are highly allergic to peanuts.
In 2020, the Food and Drug Administration approved the first treatment to induce tolerance to peanuts -– an “oral immunotherapy” named Palforzia that children ages 4 to 17 consume daily to keep up the protection. Aimmune Therapeutics' Palforzia also is being tested in toddlers.
The Viaskin patch is coated with a small amount of peanut protein that is absorbed into the skin. A daily patch is worn between the shoulder blades, where toddlers can’t pull it off., 362 toddlers with peanut allergy first were tested to see how high a dose of peanut protein they could tolerate. Then they were randomly assigned to use the Viaskin patch or a lookalike dummy patch every day.
That compares to about a third of youngsters given the dummy patches. Greenhawt said they likely include children who are outgrowing the allergy. Some youngsters also accidentally ate peanut-containing foods during the study, and researchers said allergic reactions were less frequent among the Viaskin users than those wearing the dummy patches. The most common side effect was skin irritation at the patch site.The results “are very good news for toddlers and their families as the next step toward a future with more treatments for food allergies,” Dr.
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