The eyes are more than a window to the soul — they’re also a reflection of a person’s cognitive health.
“The eye is the window into the brain,” said ophthalmologist Dr. Christine Greer, director of medical education at the Institute for Neurodegenerative Diseases in Boca Raton, Florida. “You can see directly into the nervous system by looking into the back of the eye, toward the optic nerve and retina.” Research has been exploring how the eye may help in diagnosing Alzheimer’s disease before symptoms begin. The disease is well advanced by the time memory and behavior are affected.
“These changes in the retina correlated with changes in parts of the brain called the entorhinal and temporal cortices, a hub for memory, navigation and the perception of time,” Koronyo-Hamaoui said. Investigators in the study collected retinal and brain tissue samples over 14 years from 86 human donors with Alzheimer’s disease and mild cognitive impairment — the largest group of retinal samples ever studied, according to the authors.
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