Typhoid fever might be rare in developed countries, but this ancient threat, thought to have been around for millennia, is still very much a danger in our modern world.
According to new research, the bacterium that causes typhoid fever is evolving extensive drug resistance, and it's rapidly replacing strains that aren't resistant.Currently, antibiotics are the only way to effectively treat typhoid, which is caused by the bacteriumserovar Typhi . Yet over the past three decades, the bacterium's resistance to oral antibiotics has been growing and spreading.
While most XDR Typhi cases stem from south Asia, researchers have identified nearly 200 instances of international spread since 1990. In 2016, the first XDR typhoid strain was identified in Pakistan. By 2019, it had become the dominant genotype in the nation. If untreated, up to 20 percent of typhoid cases can be fatal, and today, there are 11 million cases of typhoid a year.Future outbreaks can be prevented to some extent with typhoid conjugate vaccines, but if access to these shots is not expanded globally, the world could soon have another health crisis on its hands.
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