Research in Africa has found a one-time dose of an experimental drug protected adults against malaria for at least six months.
This 2014 photo made available by the U.S. Centers for Disease Control and Prevention shows a feeding female Anopheles funestus mosquito. The species is a known vector for malaria. The parasitic disease killed more than 620,000 people in 2020 and caused 241 million cases, mainly in children under 5 in Africa.
The new study tested a very different approach — giving people a big dose of lab-made malaria-fighting antibodies instead of depending on the immune system to make enough of those same infection-blockers after vaccination. The experimental antibody, developed by researchers at the U.S. National Institutes of Health, was given by IV — difficult to deliver on a large scale. But the encouraging findings bode well for an easier-to-administer shot version from the same scientists that’s in early testing in infants, children and adults.
The research involved 330 adults in Mali who got either one of two different antibody doses or a dummy infusion. All were tested for malaria infection every two weeks for 24 weeks. Anyone who got sick was treated.
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