Aspirin: The evolution of a 'wonder drug' that changed medicine

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Aspirin: The evolution of a 'wonder drug' that changed medicine
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A brief history of the pill that’s in everyone’s medicine cabinets.

Although aspirin was first synthesized in 1897, its antithrombotic effect wasn’t demonstrated until several studies that took place between the 1960s and the 1980s confirmed it.

After a large number of cases in children were associated with aspirin use in the early 1980s, the Centers for Disease Control and Prevention , the American Academy of Pediatrics , and the Food and Drug Administration advised against the use of aspirin-containing medications in children, which greatly reduced the incidence of the disease.found in plants, such as myrtle, meadowsweet, and willow.

The chemical structure of salicylic acid was worked out in 1859 by Professor Hermann Kolbe at Marburg University. Although successful clinical trials of the compound were later made, it had an unpleasant taste and irritated the stomach, so was rarely used. It registered the name “aspirin” on February 1, 1899, and began mass-producing it and marketing it as a pain reliever, fever reducer, and anti-inflammatory medication.

On the other hand, studies of aspirin's effects on platelets started in the 1950s, after practitioner Lawrence Craven noticed that some of his tonsillectomy patients, who were using aspirin-laced chewing gum to treat their pain, had been hospitalized due to

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