Science, Space and Technology News 2023
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Bats have acquired remarkable traits throughout their evolution. They’re the only mammals that can fly, and they live much longer than other animals their size. But perhaps most impressive is their robust immune system. It protects bats from viruses that wreak havoc in humans, likeGenomic Insights Into Bat Immunity
“We didn’t know immune system genes were so positively selected in bat genomes. Bats have a number of very unusual things about them. They don’t respond to infections the way we do. In retrospect, it’s not surprising this difference in the immune system may be involved in both the aging and cancer response.”
They also found that compared to other mammals, bat genomes contain more changes in cancer-related genes, including six that repair“Our work highlights how immunity and cancer response are deeply interconnected,” Scheben says. “The same immune genes and proteins play important roles in cancer resistance.”McCombie, Siepel, and Scheben are now exploring how bats’ immune genes are regulated and how they might be expressed in different parts of the body.
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