Developmental disruption makes people more susceptible to mental illness and drug dependence. University of California, Irvine researchers are conducting ground-breaking research into the idea that unpredictable parental behaviors, coupled with an unpredictable environment, such as a lack of routin
Developmental disruption makes people more susceptible to mental illness and drug dependence.researchers are conducting ground-breaking research into the idea that unpredictable parental behaviors, coupled with an unpredictable environment, such as a lack of routines and frequent disasters, disrupt children’s ability to develop their emotional brain circuits to their full potential, making them more susceptible to mental illness and substance abuse.
Dr. Tallie Z. Baram, corresponding author and distinguished professor in the Departments of Anatomy & Neurobiology, Pediatrics, Neurology, and Physiology & Biophysics at the University of California, Irvine, and Matthew T.
They receive numerous streams of information which promote activity of the neurons in the circuits. This activity is required for maturation of the components and refinement of the integrative connections. In early life, as these emotional circuits are developing, parents are the proximate primary environment: They are the source of information that influences the child’s brain maturation.
Studies of mice reared by dams displaying unpredictable behavior sequences during the early postnatal period show that maternal behaviors influence synaptic connectivity in key brain nodes, including those that contribute to stress. Research involving infants and children suggests that unpredictable patterns of maternal behaviors are associated with later deficits in emotional control and behaviors.
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