'I see this as the first step in developing a new strategy for repairing the brain.'
The researchers had removed parts of the rats' visual cortices, meaning that their ability to see was significantly impaired, but thanks to the "" of lab-grown neurons inserted into these damaged sections — not unlike a brain plug — some of these areas were able to spring back to life.
The three-dimensional tissue grown from human stem cells called organoids started responding to stimuli after just two months, they say — and even grew in size a little. The scientists showed the rats flashing images on a screen while measuring neuronal activity using an electrode implanted into their brains.
Using a special fluorescent liquid injected into the affected areas, the researchers were able to show that the new organoid had connected to the rats' retinas through a network of new connections. By shining bright lights at the rats, the organoids responded just as a normal virtual cortex would.
"I see this as the first step in developing a new strategy for repairing the brain," Han-Chiao Isaac Chen, senior author of a
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