For tens of thousands of patients, precisionmedicine is rewriting their cancer stories. By targeting unique tumors, precision medicine is crushing once-untreatable cancers. But only a fraction of patients currently benefit. Can medicine close the gap?
Medicine is of no use if patients don't have access to it. To get new drugs out faster, researchers are using AI to speed the process of drug development. One of the biggest causes of delay in testing new drugs is recruiting enough patients for a trial. Researchers not only need a group to try the new drug, but another"control" group to get the standard treatment, for purposes of comparison.
To give more experimental precision drugs a better shot at glioblastomas, the newly created Ivy Brain Tumor Center at the Barrow Neurological Institute in Phoenix has developed"accelerated trials" for its brain-cancer patients. A newly diagnosed patient is first given a dose of an experimental precision drug. The dose is too small to harm the patient but big enough to reach the tumor. After surgery, doctors test the tumor to see if the drug had any effect.
Payment isn't the only obstacle to treatment. About 85 percent of U.S. cancer patients get treated at a community hospital, where they see an oncologist who treats many different types of cancers. Those generalists are typically not up on the latest tests and treatments, says Caligiuri. The hospitals who employ them don't expect them to go through the time and expense of figuring it out.
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