Can an Untreated Urinary Tract Infection Really Cause Acute Psychosis?

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Can an Untreated Urinary Tract Infection Really Cause Acute Psychosis?
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“His urethra had wrested control from his brain.”

’s leading octogenarian and media-empire patriarch was shivering. He was moaning and grimacing and babbling. He was yelling—and not in the way that would actually be normal for him. He needed to pee, like bad. It got weird: He mistook his daughter for his estranged wife, and his son-in-law for an appropriate bathroom companion. He believed there was a dead cat under his chair.

Turns out, Logan had stopped taking the medication prescribed for his urinary tract infection. By the time a long-awaited shareholder meeting rolled around, Logan was fully incapacitated. “Oh, fuck!” cried his daughter, Shiv. “He’s piss-mad.”It seems like just another wild twist in the popular television drama. But Logan’s total thrashing by a UTI—leading to a state of incoherence so profound it creates a power vacuum—is totally plausible, urologists say.

UTIs occur when bacteria enter the urinary tract, and then begin to flourish out of control. The symptoms are deeply unpleasant: a persistent and frequent urge to pee, painful or burning sensations during peeing, and urine that appears cloudy, pink, red, or cola-colored. These are often enough to land someone in their doctor’s office or the emergency room, where they are given an antibiotic treatment. This usually works.

of women experience during their lifetime—don’t have to contend with further symptoms. And those worse outcomes don’t come on suddenly. “Most folks usually don’t go from nothing to an acute psychotic event,” Ginsberg says.But if—as with Logan—a person’s UTI isn’t properly treated, the infection can spread to the kidneys and, eventually, the bloodstream, becoming septic.

birthday, to last week’s episode, when he almost collapsed during a walk. Logan Roy matches some of the key risk factors for UTIs, which include being older or immunocompromised, and having dementia or diabetes. Logan’sis also potentially at play, says Ashley Winter, a urologist in Portland, Oregon who watches the show. “A stroke can affect bladder function,” she says. “It can also affect the nerves that go to the bladder, and your brain’s ability to regulate your bladder.

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