A cholesterol-lowering drug named Nexletol reduced the risk of heart attacks and some other cardiovascular problems in people who can't tolerate statins.
SAN FRANCISCO -- Drugs known as statins are the first-choice treatment for high cholesterol but millions of people who can't or won't take those pills because of side effects may have another option.
Statins remain"the cornerstone of cholesterol-lowering therapies," stressed Dr. Steven Nissen of the Cleveland Clinic, who led the study. But some people suffer serious muscle pain from statins. While it's not clear exactly how often that occurs, by some estimates 10% of people who'd otherwise qualify for the pills can't or won't take them. They have limited options, including pricey cholesterol-lowering shots and another kind of pill sold as Zetia.Nexletol also blocks cholesterol production in the liver but in a different way than statins and without that muscle side effect.
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