Rates of Alzheimer's disease are higher in women than in men, and researchers now think they know why:
Research suggests that tau spreads through the brain like an infection, moving from neuron to neuron and turning other proteins into abnormal tangles that result in the death of brain cells.
"It's kind of like reconstructing a crime scene after a crime. You weren't there when it happened, but you can determine where an intruder entered a house and what room they entered next," said lead investigator Sepi Shokouhi, an assistant professor of"The graph analysis does something similar to show how tau spreads from one region to another," Shokouhi explained in a center news release.
This may enable tau to spread more easily between brain regions, increasing the speed at which it accumulates and putting women at greater risk for Alzheimer's disease, the investigators theorized.
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