The Colts have ruled out their top two running backs against the Jaguars, setting a second-year undrafted player up to be the top back.
The Colts are going to be without their top two running backs for a second straight game.
That means undrafted second-year back Deon Jackson will take the bulk of the backfield workload. The Colts have also elevated running backs Phillip Lindsay and D'Vonte Price from the practice squad, as well as wide receiver Keke Coutee. They waived tackle Luke Tenuta.
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