Experts are now looking into the use of Ozempic as a form of medication in the treatment of addiction.
New medications could work by interrupting the reward circuit in the brain. Alcohol use disorder, the medical diagnosis for alcoholism, affects about 10 percent of the U.S. population, or. Yet, doctors wanting to treat this condition have only a handful of medications at their disposal, including such drugs as disulfiram, Acamprosate and naltrexone.
Disulfiram makes people violently ill if they drink. Acamprosate is powerfully tranquilizing. And naltrexone suppresses the opioid system, which can reduce cravings in both alcoholics and opiate users. Still, doctors rarely prescribe these drugs, as only about 5 percent of patients in the U.S. take one of them.
They’re often seen as inferior to the life-changing psychosocial interventions normally recommended. But experts are now looking into the use of Ozempic as a form of medication in the treatment of addiction.They’re called GLP-1 agonists, and they include the popular diabetes drug Ozempic – heavily prescribed off-label for weight loss – and its cousin, Wegovy, approved in 2021 for the same purpose.
. And high interest in semaglutide, the active ingredient in both, has led to shortages, despite their high price tags. Wegovy can cost upwards of $1,300 a month without insurance. Ozempic works on a few different fronts to reduce weight: It stimulates the pancreas to release more insulin, slows digestion and appears to bind to receptors in the brain that are connected to the all-important reward system. By altering dopamine activity there, it may reduce cravings to eat.This same mechanism could stem all manner of addictions, from nail biting to alcohol use, but more research is needed.
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