It will be a long time before this type of epigenetic remodeling is available to regular patients. 🤓
published Wednesday in the peer-reviewed journal“Early binge drinking can have long-lasting and significant effects on the brain, and the results of this study offer evidence that gene editing is a potential antidote to these effects, offering a kind of factory reset for the brain, if you will,” says psychiatrist and epigeneticistThe sequence of DNA — the exact ordering of A, T, C, and G — isn't the whole story.
The researchers behind the new study gave a group of four- to six-week-old rats access to alcohol in a simulation of. In some of the rats, they used a gene-editing tool called CRISPR-dCas9 to physically manipulate the DNA in an attempt to reverse the changes caused by the drinking. Then they put their subjects to the test. The rats that had undergone"epigenetic remodeling" were better at mazes and less inclined to drink alcohol than rats that didn't receive any treatment at all.This study advances the science around alcohol abuse in a couple of ways. First, it confirms the relationship between teenage bingeing and the ARC gene. It also provided evidence of a fix, though it will probably be a long time before such treatment is available for humans.
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