The CDC estimates that XBB.1.16 is now more than 1 in 10 infections.
Scientists say XBB.1.16 is relatively similar to previous strains that have recently been dominant in the United States, including thethat drove the last wave of infections this past fall and winter, and does not seem to be leading to worse or different symptoms compared to other variants.
"We have not observed a dramatic shift in spike since that Delta to Omicron shift," the Centers for Disease Control and Prevention's Dr. Natalie Thornburg said at an April 27 vaccinesThornburg said XBB.1.16 has only a handful of mutations on SARS-CoV-2's spike protein compared with its recent predecessors, fewer than the more than two dozen changes seen when the original Omicron strains overtook other variants earlier in the pandemic.
XBB.1.16 could be on track to outcompete another variant called XBB.1.9, which makes up 12.7% of circulating virus across the U.S. But XBB.1.16 is also similar enough to its siblings thata single vaccine recipe might be able to boost against all of them this fall. "We have continued to see accumulating substitutions in the spike protein more incrementally over time. And that can be described as drift, which happens more slowly," said Thornburg.How many people have infections from this COVID variant?
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