Dozens of drugmakers are conducting human trials for a record 89 therapies that ...
) bladder cancer drug, Padcev, also received expedited approval in December, based on evidence that 44% of patients who had failed immunotherapy showed improvement, and in some cases, no evidence of cancer, when they were assessed after treatment.
The number of ADC drug candidates is at unprecedented levels, according to data from consultancy Beacon Targeted Therapies compiled for Reuters, based on a review of companies’ pipelines. Dozens more ADC prospects are in pre-clinical review. Current ADC projects include GlaxoSmithKline testing its belantamab mafodotin against multiple myeloma.
U.S. biotech Immunomedics’ market capitalization gained more than 60% to $4.3 billion in the last six months, ahead of the U.S. Food and Drug Administration’s late-December decision to review its ADC against triple-negative breast cancer, which is hard to treat and has poor prognosis.
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