Drug pipeline 1Q23 — Everything everywhere all over the place - Nature Biotechnology

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Drug pipeline 1Q23 — Everything everywhere all over the place - Nature Biotechnology
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Our 1Q23 drug pipeline Data Page shows three approvals for treatments for rare diseases: ChiesiGroup’s Lamzede for α-mannosidosis, AcadiaPharma's Daybue for Rett syndrome and ReataPharma's Skyclarys for Friedreich’s ataxia

Leqembi /Eisai, Biogen

1/6/2023 FDA gives accelerated approval to this humanized monoclonal IgG1 antibody against amyloid-β plaques3/10/2023 FDA approves this analog of the amino-terminal tripeptide of IGF-12/28/2023 FDA approves this small-molecule activator of Nrf2, which activates genes that promote mitochondrial function2/23/2023 FDA approves this fully recombinant extended-half-life factor VIII protein that can be dosed once-weekly1/27/2023 FDA grants accelerated approval for this small-molecule BTK inhibitor...

IgG, immunoglobulin G; IGF-1, insulin like growth factor 1; Nrf2, nuclear factor erythroid 2–related factor 2; BTK, Bruton’s tyrosine kinase; PD-1, programmed cell death 1; mAb, monoclonal antibody; SGLT2, sodium–glucose transporter 2. Source: BioMedTracker, a service of Sagient Research (

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