'Many studies ... have suggested that patients with cancer don't create a strong immune response, and this is the first large study that likely shows the consequences of this,.'
- The following is a summary of some recent studies on COVID-19. They include research that warrants further study to corroborate the findings and that has yet to be certified by peer review.
The researchers first performed these antigen tests on swab samples from 181 individuals with PCR-confirmed SARS-CoV-2 infections. Next, they took the virus from the swabs and tried to grow it in test tubes. When viral loads were below the antigen tests' level of detection, the virus particles were often incapable of growing.
People with low viral loads and negative antigen tests may become infectious "a day or two or three days later," said Dr. James Kirby of Beth Israel Deaconess Medical Center in Boston. "Therefore, to be most effective, antigen tests should be used immediately before an event or contact with those at greater risk from infection." The swabs must be collected for testing carefully, following the instructions provided with the testing kits, he added.
Among 54 cancer patients who became infected despite receiving a two-dose vaccine from Moderna or Pfizer/BioNTech or a single-dose vaccine from Johnson & Johnson - before booster doses were recommended - 65% needed to be hospitalized, 19% ended up in intensive care units, and 13% died, according to data from the international COVID-19 and Cancer Consortium.The study did not analyze the vaccines' efficacy at preventing infections in the first place.
"Many studies ... have suggested that patients with cancer don't create a strong immune response, and this is the first large study that likely shows the consequences of this," said Dr. Jeremy Warner of Vanderbilt University in Nashville, Tennessee. "Additional doses and boosters are critical, as are continued masking, social distancing, and encouragement of all close contacts of patients with cancer to get vaccinated.
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