Sponsored by the National Institutes of Health, the study will test up to 11 combinations of treatments for long COVID.
Organizers are not looking for a cure for COVID. They aim to learn why long COVID happens, both to stop future cases and to help those already experiencing debilitating symptoms.
The first phase of the study, which included 24,000 patients, involved observing people with long COVID to see when and why symptoms develop. Phase two, now starting at NorthShore, includes three clinical trials targeting cognitive dysfunction, sleep issues and viral particles. The third section of the trials, Recover-Sleep, will compare two different medications that could be used to stop excessive daytime sleepiness. Other proven interventions for problems falling or staying asleep will be tested in groups.
Cates, 52, contracted COVID for the first time in March 2023. What felt like a bad cold developed into a “heavy feeling” that reminded Cates of pneumonia. Within a month, her heart was racing constantly, an early sign of long COVID. The team initially reached out to 2,000 potential long COVID patients in the Chicago area, Shah said. Between 50 and 75 people responded.
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