An experimental Eli Lilly drug slowed cognitive and functional decline for people with early-stage Alzheimer’s disease in a new study that could support regulatory approval and commercial sale
that was among the first to significantly slow the worsening of the memory-robbing disease, after years of failed attempts by the drug industry to find such drugs.
In the study of more than 1,730 patients, the drug slowed patients’ decline by 35% compared with people who received a placebo over 18 months of treatment, Lilly said. “These are levels of efficacy that just haven’t been seen before in Alzheimer’s, setting a new benchmark for what’s possible in this disease,” Dr. Skovronsky said.
About 1.6% of the abnormalities were classified as serious, including two people who died from them and a third person who died after an abnormality, Lilly said.from a smaller, midstage study in 2021. Based on that study, Lilly applied for approval from the FDA. The agency said it needed more data before it could make a decision.
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