Researchers unveil a new method to visualize cell organization. Working with hundreds of thousands of high-resolution images, researchers from the Allen Institute for Cell Science, a division of the Allen Institute, put numbers on the internal organization of human cells — a biological concept that
Integrated average morphed cell showing 17 select structures. Credit: Allen Institute for Cell ScienceWorking with hundreds of thousands of high-resolution images, researchers from the Allen Institute for Cell Science, a division of the, put numbers on the internal organization of human cells — a biological concept that has proven incredibly difficult to quantify until now.
Understanding how cells organize themselves under healthy conditions — and the full range of variability contained within “normal” — can help scientists better understand what goes wrong in disease. The image dataset, genetically engineered stem cells, and code that went into this study are all publicly available for other scientists in the community to use.
The team ran into a challenge comparing the same structure between two different cells. Even though the cells under study were genetically identical and reared in the same laboratory environment, their shapes varied substantially. The scientists realized that it would be impossible to compare the position of structure A in two different cells if one cell was short and blobby and the other was long and pear-shaped. So they put numbers on those stubby blobs and elongated pears.
If you’re looking at how thousands of white-collar workers arrange their furniture in a high-rise office building, it’s as if every worker put their desk smack in the middle of their office and their filing cabinet precisely in the far-left corner, no matter the size or shape of the office. Now say you found one office with a filing cabinet thrown on the floor and papers strewn everywhere — that might tell you something about the state of that particular office and its occupant.
México Últimas Noticias, México Titulares
Similar News:También puedes leer noticias similares a ésta que hemos recopilado de otras fuentes de noticias.
GOT1 constrains TH17 cell differentiation, while promoting iTreg cell differentiation - NatureMatters arising: GOT1 constrains TH17 cell differentiation, while promoting iTreg cell differentiation
Leer más »
A Beginner's Guide to Data Structures and Algorithms | HackerNoonData structures and algorithms allows you to write better code, solve complex problems, and understand the inner workings of computer programs. - by iamdeewyne programming datastructuresandalgorithms
Leer más »
'Black on Black' celebrates Black culture while exploring history and racial tensionDaniel Black’s collection of essays call for an overhaul of the U.S. criminal justice system, of the way Black people see themselves and more. They aren’t an easy read, but his strong, informed, relentless voice affects readers, our critic writes.
Leer más »
'My Animal' Filmmakers on Exploring Being an Outsider via a Werewolf StoryBobbi Salvör Menuez, Jacqueline Castel & Jae Matthews tell us all about exploring being an outsider via a werewolf story with MyAnimal:
Leer más »
Exploring The New Beauty CounterThree cutting-edge companies on how emerging technologies and digital platforms are transforming social and e-commerce shopping.
Leer más »
Lakers still exploring ways to improve with potential Russell Westbrook dealFor teams searching to upgrade ahead of Thursday's NBA trade deadline — which, to be clear, still stands as the overwhelming majority of the league's 30 clubs — forecasting potential additions for any playoff hopeful is really an exercise of process of elimination.
Leer más »