FDA advisers consider changing COVID vaccine to target latest omicron strain

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FDA advisers consider changing COVID vaccine to target latest omicron strain
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The COVID-19 vaccines are on track for a big recipe change this fall

. Scientific advisers for the Food and Drug Administration on Thursday, June 15, 2023, discussed whether the next round of shots should only include protection against the newest omicron strains that are now dominant worldwide. Today’s vaccines still contain the original coronavirus strain, the one that started the pandemic — even though that was long ago supplanted by mutated versions as the virus rapidly evolves.

“We’re concerned that we may have another wave of COVID-19 during a time when the virus has further evolved, immunity of the population has waned further, and we move indoors for wintertime,” he said.The FDA told Americans to expect an updated fall vaccine against COVID-19, just like they get a new flu shot every fall. Even though most of the population has either been infected or had at least one round of vaccinations, the coronavirus keeps churning out new varieties.

Those currently available shots do still help prevent severe disease and death even as XBB variants have taken over. But protection gradually wanes over time and was short-lived against milder infection even before the virus, inevitably, evolved again.Last year when regulators were struggling to decide how to update the vaccine, a combo shot seemed like the safest bet.

So the FDA is leaning toward dropping the original strain and picking a fall shot recipe that targets just XBB. The hope is that the XBB variants are different enough to spark the immune system to make more diverse, cross-protective virus-fighting antibodies.

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