FDA OKs mixing COVID-19 vaccines, backs Moderna and Johnson & Johnson boosters

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FDA OKs mixing COVID-19 vaccines, backs Moderna and Johnson & Johnson boosters
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U.S. regulators are extending COVID-19 boosters to Americans who got the Moderna or Johnson & Johnson vaccine.

— making it simpler to get another dose, especially for people who had a side effect from one brand but still want the proven protection of vaccination.

Specifically, the FDA authorized a third Moderna shot for seniors and others at high risk for COVID-19 because of their health problems, jobs or living conditions, as long as it’s been at least six months since their last shot.One big change: Moderna’s booster will be half the dose that’s used for the first two shots, based on company data showing that was plenty to rev up immunity again.

For J&J’s single-shot vaccine, the FDA said all U.S. recipients, no matter their age, should get a second dose at least two months following their initial vaccination. The FDA decisions differ because the vaccines are made differently, with different dosing schedules — and the J&J vaccine has consistently shown a lower level of effectiveness than the two-shot Moderna and Pfizer vaccines.Approving COVID-19 booster shots seemed like a slam dunk, but two influential advisory boards raised a host of complicated questions.

As for mixing and matching, the FDA said it’s OK to use any brand for the booster regardless of which one people got first. The interchangeability of the shots is expected to speed the booster campaign, particularly in nursing homes and other institutional settings where residents have received different shots over time.

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