Between 2010 and 2016, there has been a 493 percent spike in people being diagnosed with opioid addiction, in what the National Institute of Drug Abuse describes as a national crisis.
A vaccine against fentanyl—a drug contributing to the opioid crisis gripping the U.S.—appears to have put rats off the substance in a study.
Dr. Matthew L. Banks, associate professor of pharmacology and toxicology at VCU School of Medicine, and professor Kim D. Janda of The Scripps Research Institute co-authored a study published in the journal Neuropsychopharmacology. The scientists created a vaccine designed to stop rats from craving fentanyl by triggering an immune response against the drug. To test it, they dosed mice addicted to fentanyl twice over a three-week period, with either the experimental vaccine or two medications currently used to treat substance addiction . The team documented whether the rats would seek out fentanyl or food after taking the medicine.
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