While previous pig organ transplants modified as many as 10 genes, this recent procedure centers on the removal of a single gene in the pig kidney.
“We’ve now gathered more evidence to show that, at least in kidneys, just eliminating the gene that triggers a hyperacute rejection may be enough along with clinically approved immunosuppressive drugs to successfully manage the transplant in a human for optimal performance—potentially in the long-term,” said Dr. Montgomery.
The researchers will continue to monitor the transplanted kidney's overall performance until mid-September 2023.engineered by Revivicor, IncThe use of GalSafe pig was officially approved by the US Food and Drug Administration in December 2020. Its applications include human therapeutics and as a dietary source for those suffering from alpha-gal syndrome, a meat allergy caused by a tick bite.
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