In adults with cirrhosis and type 2 diabetes, glucagon-like peptide-1 receptor agonist therapy significantly lowered the risk for death and other adverse outcomes, a study found.
Population-based cohort study using data from the National Health Insurance Research Database of Taiwan.
Propensity-score matching was used to construct 467 matched pairs of GLP-1 RA users and nonusers with T2D and compensated liver cirrhosis. All-cause mortality, cardiovascular events, decompensated cirrhosis, and other key outcomes were compared using multivariable-adjusted Cox proportional hazards models.During mean follow-up of about 3 years, rates of death per 1000 person-years were 27.5 in GLP-1 RA users versus 55.9 in nonusers.
GLP-1 RA users had a significantly lower risk for mortality , cardiovascular events , decompensated cirrhosis , hepatic encephalopathy , and liver failure . A longer cumulative duration of GLP-1 RA use was associated with lower risk for these outcomes compared with no use."GLP-1 RAs may be a treatment option for diabetes patients with liver cirrhosis. However, additional studies are needed to confirm our results and to explore the mechanisms of GLP-1 RAs, cirrhotic decompensation and hepatic encephalopathy," the researchers conclude.
México Últimas Noticias, México Titulares
Similar News:También puedes leer noticias similares a ésta que hemos recopilado de otras fuentes de noticias.
'Titanic' Heralded the End of a Very Specific Type of Hollywood BlockbusterTitanic was the end of an era for the romantic epic, even if audiences didn't know it at the time.
Leer más »
A 360-Degree Examination of Type 1 Diabetes: From Patient Identification to Treatment and Prevention➡️ Learn how to identify those at risk for type 1 diabetes, how to stage T1D, and when and how to start interventions that can slow the progression of disease. CME 📝 Learn by clicking the link.
Leer más »
Jennifer Lopez Goes Furniture Shopping in an Inspiring Graphic TeeGetting a different type of inspo from this casual look
Leer más »
Could giant building blocks help LA's homeless crisis?Architect Charles Wee, the founder of LifeArk, created the blocks to help the housing crisis by quickly making homes that are safe, sustainable and affordable
Leer más »
How AI could help Gen Z to succeed in the workplaceInsider tells the global tech, finance, markets, media, healthcare, and strategy stories you want to know.
Leer más »
Glendale police looking for public help identifying stabbing suspectDO YOU RECOGNIZE HIM? Glendale police are trying to identify this man, saying he reportedly stabbed a woman at Murphy Park in early June.
Leer más »