Gonorrhea shot gets FDA fast track as resistant cases multiply

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Gonorrhea shot gets FDA fast track as resistant cases multiply
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The fast-track designation puts the shot in position to become the first preventive for a common, often-undetected infection that’s gaining resistance to treatment.

Matthew Griffin | Bloomberg News

In 2020, some 82 million people worldwide caught gonorrhea, a sexually transmitted infection that can lead to complications including infertility. While some patients show early symptoms, such as pain or urethral discharge in men or vaginal discharge in women, many cases may be missed even as the disease does long-term damage.

The threat of gonorrhea, along with other sexually transmitted diseases like syphilis and chlamydia, is on the rise around the world. Cases hit a record high in England last year. In the U.S., the rate of reported infections more than doubled between 2009 and 2021. Already, there are signs that ceftriaxone may have its limits. In January, Massachusetts public health officials reported the first U.S. patient infected by a strain showing reduced susceptibility to all recommended gonorrhea therapies.

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