“Good” and “bad” cholesterol: These well-known characters have long starred in the saga of heart health.
, and it contributes to inflammation. The fact that HDL’s roles can change, depending on the context, has made studying HDL particles challenging, Rohatgi says.
In the new study, the team analyzed data from the REGARDS trial, designed to study potential regional and racial differences in death from stroke in the United States. The study included nearly 24,000 participants — of which 42 percent were Black — who did not start out with coronary heart disease. Over roughly 10 years, 664 out of 10,095 Black participants and 951 out of 13,806 white participants had a heart attack or died from one.
Rather than just good, HDL cholesterol “is complicated,” she says. If a patient has high HDL cholesterol, a doctor “can say, ‘well, currently we don’t know what that means.’” Some of the risk factors for coronary heart disease, including high blood pressure and smoking, “are more prevalent in self-described Black Americans,” he says. And a
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