A team from the Dalian Institute of Chemical Physics has pioneered a microbial system that optimizes the production of valuable chemicals from lignocellulosic biomass by enhancing sugar co-fermentation. Lignocellulosic biomass is a renewable feedstock for 2nd-generation biomanufacturing. In parti
Fatty acids and 3-hydroxypropionic acid were efficiently produced by engineering co-utilization of glucose and xylose in Ogataea polymorpha for lignocellulose biorefinery. Credit: DICP
A team from the Dalian Institute of Chemical Physics has pioneered a microbial system that optimizes the production of valuable chemicals from lignocellulosic biomass by enhancing sugar co-fermentation.-generation biomanufacturing. In particular, efficient co-fermentation of mixed glucose and xylose in lignocellulosic hydrolysates is a key issue in reducing product costs.
However, co-utilization of xylose and glucose in microbes is challenging due to limited xylose assimilation and the glucose repression effect.Recently, a research group led by Prof. Yongjin Zhou from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences has proposed a microbial platform for lignocellulose bio-refinery.
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