Studies suggest the J&J vaccine may provide somewhat less protection, particularly against the delta variant, which now accounts for more than 80% of COVID-19 cases across the United States.
, public health officials emphasized that it was just as good as the others. It was less effective, but because it requires only a single shot for full protection and is easier to distribute, it was a top choice for many people.
"Johnson & Johnson is not a bad vaccine – it’s way better than getting nothing," said Dr. Otto Yang, an infectious disease specialist at UCLA Health. "But it’s not as good as other options."The J&J vaccine looks second-class only because the other two vaccines are so good, experts say. All the COVID-19 vaccines carry a small risk of an allergic reaction – two to five people per million – and the mRNA vaccines bring a slight risk of myocarditis, a swelling of the heart, particularly in younger men and adolescents, though most of those cases have been mild.
"I’m wanting to do more things besides all of my outdoor activities but I'm too scared!" said Jill Oliver, a J&J recipient from Boulder, Colorado. Although J&J studies show their vaccine offers continued protection against most of the known variants, abut not yet peer-reviewed suggested it was less effective against the delta variant. Researchers from New York University, who declined to be interviewed, found that blood samples from people who had received the J&J vaccine were less able to neutralize the delta variant than blood from people who received the Pfizer-BioNTech or Moderna shots.
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