Is Long COVID Really 'Long Everything'?

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Is Long COVID Really 'Long Everything'?
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LongCOVID is real, but whether this syndrome is a unique sequela of SARS-CoV-2 infection is another question. MedicalNews

, your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson of the Yale School of Medicine.

But is this postillness syndrome unique to COVID infection? Or have we simply failed to understand that in reality, there is long everything? Patients hospitalized with COVID are quite different from those hospitalized with flu or sepsis. They are substantially younger, with a mean age of 61 compared with 74 or 75. They are less likely to be female; it has become quite clear that men tend to do worse with COVID than do women. It's worth noting that only 15.3% of the COVID group had received a dose of vaccine, compared with 35% of the sepsis group hospitalized during the pandemic.

The researchers used something called"propensity score overlap weighting" to account for the baseline differences among patients as well as for the stuff that happened during the hospitalization — essentially accounting for the particular severity of COVID. This is a rather novel method to account for traditional confounders, which I really like and my lab has used in aOkay, the big question.

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