Israeli doctors find severe COVID-19 breakthrough cases mostly in older, sicker patients

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Israeli doctors find severe COVID-19 breakthrough cases mostly in older, sicker patients
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In Israel's COVID-19 wards, doctors are learning which vaccinated patients are most vulnerable to severe illness, amid growing concerns about instances in which the shots provide less protection against the worst forms of the disease.

Around half of the country's 600 patients presently hospitalized with severe illness have received two doses of the Pfizer IncThe majority of these patients received two vaccine doses at least five months ago, are over the age of 60 and also have chronic illnesses known to exacerbate a coronavirus infection.

Other countries, including France and Germany, have so far limited their booster plans to the elderly and people with weak immune systems. Disease experts say it is not clear how representative the figures are, but agree it is concerning given evidence that overall vaccine protection against infection is waning.

"We are watching other countries carefully and concerned that we too will see what Israel is seeing, which is worsening infections over time" among vaccinated people, U.S. Centers for Disease Control and Prevention Director Rochelle Walensky said at a press conference on Wednesday. "For some of them the vaccine did not trigger an immune response, they had no antibodies, because of the illness itself or because they are treated with medication that suppresses the immune system," said Dror Mevorach, who heads the coronavirus ward at Hadassah hospital in Jerusalem. He cited examples such as chronic lymphocytic leukemia and lymphoma.

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