Jimmy Garoppolo threw four touchdown passes, including two each to Brandon Aiyuk and George Kittle.
MEXICO CITY — Jimmy Garoppolo threw four touchdown passes, including two each to Brandon Aiyuk and George Kittle, and the San Francisco 49ers won their third straight game by blowing past the Arizona Cardinals 38-10 on Monday night in Mexico City.
San Francisco has won five of its last seven and is tied with the Seahawks at the top of the NFC West. Garoppolo had another efficient performance, completing 20 of 29 passes for 228 yards. The Cardinals played their second straight game without Pro Bowl quarterback Kyler Murray, who has been battling a sore hamstring. Backup Colt McCoy had a 3-1 record in spot starts over the past two seasons — including a win over the Rams last week — but couldn’t recreate the same magic in Mexico.McCoy finished 24 of 34 passing for 218 yards and an interception.
The Cardinals pushed ahead 3-0 midway through the first quarter on Matt Prater’s 40-yard field goal as both teams dealt with a steady rain that started around kickoff and continued through much of the first half.The 49ers responded early in the second when Garoppolo hit Aiyuk over the middle for a 7-yard touchdown, capping a nine-play, 82-yard drive. San Francisco intercepted McCoy on the ensuing drive after a pass bounced off James Conner’s hand and was snatched out of the air by Jimmie Ward.
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