The pills appeared to lower testosterone levels without adverse side effects.
To elaborate,"the progestogenic function serves to lower the pituitary production of gonadotropin hormones . Inhibiting LH leads to lower testosterone in the testis," according to Blithe and Jacobsohn.
Among the participants, 75 percent of the men who took the active drug said that they would be willing to use it in the future, in comparison with 46.4 percent of those who took the placebo.It was also observed that men who took the four-pill daily dose had lower levels of testosterone than those taking the two-pill, 200-milligram dose. that lowering testosterone levels can lead to unpleasant and serious side effects, many researchers favor contraceptives that use hormones.
"No [non-hormonal medication] has successfully transitioned to clinical evaluation, but progress is being made toward that goal. It cannot be assumed that non-hormonal methods will be free of side effects, so we will have to wait for those clinical trials to begin to see if anything emerges that was not evident in pre-clinical qualifying studies," Blithe and Jacobsohn said.
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