Loss of Y chromosome in men promotes cancer growth, new study finds

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Loss of Y chromosome in men promotes cancer growth, new study finds
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Scientists have found the first solid evidence indicating a connection between the loss of the Y chromosome and tumor growth in men with aging.

“If it is missing we can say that these patients will be more likely to respond to “immune checkpoint inhibitors” treatment,” he added.Men have XY as sex chromosomes, and women have XX. So when the researchers say

The study authors realized that the Y chromosome regulates the expression of specific genes in many body cells, including those which make up the bladder. Surprisingly, cancer was found to be growing at a faster rate in mice whose tumor cells lacked the Y chromosome. “These results imply that when cells lose the Y chromosome, they exhaust T-cells. And without T-cells to fight cancer, the tumor grows aggressively,” said Theodorescu.The main limitation of the current study is that it has shown the connection only about. There is a great possibility that Y chromosome loss is also linked to other cancer types.

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