Tim Anderson and Yoán Moncada each had three hits for the White Sox, who had lost three straight and four of five. Dylan Cease pitched six shutout innings.
Chicago went ahead to stay with two runs in the eighth against Rafael Montero . Moncada hit a leadoff double and scored on Robert's liner to right. Seby Zavala added a two-out RBI single for a 3-1 lead.
Houston threatened in the first, loading the bases with two out, but Cease escaped the jam when Peña bounced into a fielder's choice.
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