Nanoneedle breakthrough gives hope for cheaper cancer treatment

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Nanoneedle breakthrough gives hope for cheaper cancer treatment
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Australian scientists have successfully found a way to inject beneficial genetic material into white blood cells in a world-first breakthrough that could significantly improve treatment options for certain types of blood cancer.

A multidisciplinary team led by ARC Future Fellow Dr. Roey Elnathan, from Deakin University's School of Medicine, and ARC Laureate Professor Nicolas Voelcker, from Monash University's Institute of Pharmaceutical Sciences , has harnessed the power of nano-injection technology to improve outcomes in one of the world's newest forms of cancer immunotherapies, CAR-T cell therapy.

Dr. Elnathan said there was an urgent need for a scalable, affordable, streamlined CAR-T cell manufacturing process that did not rely on viral vectors. "We have already shown that our nano-injection platform can re-engineer cells that benefit patients in vitro . We now need to test this technology at a clinical level."

Deakin and Monash universities are collaborating with ULVAC Inc. in Japan to scale up fabrication of the nano-injection, which will be critical for scaling the new technology.

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