Nature’s 10

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Nature’s 10
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Nature's 10: An Omicron investigator, a Mars explorer and an AI ethics pioneer are some of the people who helped to shape science in 2021

By Richard Van Noorden

It was the first of a series of accessible, rapid explainers from Kall on dozens of the agency’s coronavirus briefings.— prepared and posted around her day job — she became a human face for a government team that has provided many early answers to burning questions about COVID-19 in 2021. With so much misinformation and confusion about what data such as these can mean, public-health agencies struggled to get their messages across. Kall stepped into this breach. “Meaghan has been a wonderful source of hot-off-the-presses information and has done a fantastic job in breaking down the reports,” says Kilpatrick.

Before COVID-19, Kall spent a decade monitoring HIV infections for UK government agencies. She says that her work with people with HIV — she was writing up her PhD on a national survey of those living with the virus when COVID-19 struck — gave her experience in understanding people’s sometimes opposing views, as did her upbringing in a small, conservative town in Michigan.

Others were less laudatory: 31 advocacy organizations urged the secretary of the US Department of Health and Human Services to keep Woodcock’s time at the helm of the FDA brief. “Dr Woodcock presided over one of the worst regulatory agency failures in US history,” they wrote, laying partial responsibility for the country’s raging opioid crisis at her feet. The debates over her would continue through a tumultuous year at the top of the agency.

A panel of external advisers to the FDA voted against the approval, but the agency made the unusual decision to ignore the recommendation. Michael Carome, director of health research at the consumer advocacy group Public Citizen in Washington DC, says it was a pivotal moment: the agency had approved a drug that could be taken by millions, without solid evidence that it helps people. “It was one of the worst decisions the agency has ever made,” says Carome.

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