This crazy bacteria feeds on nicotine.
The researchers examined nicotine accumulation in the stool and serum samples of two groups. The first group included 30 individuals who were, and the second group incorporated the same number of non-smokers. They observed a high concentration of addictive chemicals inside the samples that were taken from smokers.
Then the researchers performed a similar experiment with mice. They exposed one group of mice to nicotine and compared nicotine levels in their serum and stool samples with another group of normal mice. Again, nicotine levels were found to be higher in mouse models that were exposed to nicotine.The authors suggest that high amounts of nicotine in mice's bodies also made them more likely to develop NAFLD.
When nicotine levels were compared between the two, mice in the former group were found to have lower amounts of the addictive chemical. These results indicated that gut microorganism somehow reduces nicotine concentration in mice. Since the gut of the mouse models comprised a variety of microorganisms, the researchers had to screen their whole gut microbiota to identify the one that contained genes for nicotine-degrading enzymes.
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