Experimental neuralcelltherapy has shown promising results in reducing seizures in drug-resistant mesial temporal lobe epilepsy patients by over 90%. ➡️ More about this first-in-human test of the novel therapy: EpilepsyTreatment
An experimental neural cell therapy is safe and led to greater than 90% reduction in seizures in two patients with drug-resistant mesial temporal lobe epilepsy in the first-in-human test of the novel therapy.
NRTX-1001 therapy is a one-time dose of an injectable suspension of high-purity inhibitory interneurons that secrete the inhibitory neurotransmitter gamma-aminobutyric acid . This therapy is"potentially restorative instead of just destructive, like epilepsy surgery," study investigator David Spencer, MD, professor of neurology and director of the Comprehensive Epilepsy Center, Oregon Health & Science University in Portland, said during a press briefing.
To date, there have been no serious or unexpected adverse events from the implant. At 9 months of follow-up the patient has had a 93% reduction in seizures overall and is free of all seizures causing impairment of awareness,"which was the most debilitating seizure type for this patient," Spencer noted.
Five months after treatment, the patient has had a 94% reduction in seizures and no serious adverse events.Epilepsy affects about 3.5 million people in the United States. About two thirds of people with epilepsy get good control of their seizures using anti-seizure medication.
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