Breaking news: A male birth-control drug shows promise in mice, a study says, a possible advance in the long quest for better male contraceptives
take weeks or months of treatment to start working — and for the effects to reverse. That may be attractive for some men, but not for“The twist they have with this paper is that … they’re trying to develop an on-demand male contraceptive agent. I think that’s a really exciting way of thinking about it,” said Gunda Georg, a professor of medicinal chemistry at the University of Minnesota, who is also working on male contraceptives.
Jochen Buck, who co-directs the Weill Cornell laboratory with Levin, said it became clear nearly two decades ago that sAC played an essential role in sperm activation, and there had been initial interest from drug companies. But he said that interest waned over the subsequent 15 years.Pharmaceutical interest in developing new contraceptives has lagged for a variety of reasons, several scientists said.
rather than an injection. They founded a start-up company, called Sacyl Pharmaceuticals, to help move the research forward once they have settled on the best version. “My wife is an OB/GYN, and there’s a lot of concern,” he said. “What I hear from my wife’s colleagues is: ‘Hurry.’ It’s changed the landscape in many, many ways.”Georg’s lab at the University of Minnesota made a nonhormonal contraceptive in 2015 that will likely be tested in men for the first time later this year.
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