Scientist warns longer trips to Mars could have worse effects on astronauts' microbiomes

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Scientist warns longer trips to Mars could have worse effects on astronauts' microbiomes
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Researchers are looking for a ‘master switch’ that could change your body in space.

David Pearce is a bioscience researcher at Northumbria University and an author of a 2022 paper examining how a space trip might affect microbes in the gut. He is now trying to evaluate whether astronauts will enter a state called dysbiosis, in which their microbiome changes in significant, possibly dangerous ways.

The main question they focused their efforts on was: "Is there a master switch that could be changing your entire body in space?""As we kept analyzing, certain biological patterns kept popping up," Afshin Beheshti, the co-author of the study and researcher and bioinformatician at NASA for the GeneLab Project, said at the time."The mitochondria was surprising because that wasn't really on my radar, but it connects a lot of these things together.

Isolation, lack of gravity, cosmic radiation, and challenges of performing and executing medical care at great distances from the Earth are on the list.Pearce also argues that there's a need for more information about individual astronauts and their microbial equilibriums. It's currently not possible to evaluate how the human microbiome would change on a long trip to Mars compared to a relatively short stay on the International Space Station, Pearce said.

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