The research helps understanding of the earliest moments of life and the reasons behind infertility.
A stem-cell derived human embryo model showing blue cells , yellow cells and pink cells .Scientists have grown an entity that closely resembles an early human embryo, without using sperm, eggs or a womb.
"This is really a textbook image of a human day-14 embryo," Prof Hanna says, which "hasn't been done before". About 1% of the mixture began the journey of spontaneously assembling themselves into a structure that resembles, but is not identical to, a human embryo. I can see the trophoblast, which would normally become the placenta, enveloping the embryo. And it includes the cavities - called lacuna - that fill with the mother's blood to transfer nutrients to the baby.
There is even talk of improving in vitro fertilisation success rates by helping to understand why some embryos fail or using the models to test whether medicines are safe during pregnancy. But the current 99% failure rate would need to be improved, he adds. It would be hard to understand what was going wrong in miscarriage or infertility if the model failed to assemble itself most of the time.The work also raises the question of whether embryo development could be mimicked past the 14-day stage."Some will welcome this - but others won't like it," Prof Lovell-Badge says.
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