While both protect from severe disease, inactivated SARS-CoV-2 and spike mRNA COVID-19 vaccines trigger different T-cell responses. Although the total magnitude of the T-cell responses induced by mRNA and inactivated SARS-CoV-2 vaccines are comparable, the similarity ends there. This is according
A new study reveals key differences in immune responses from inactivated SARS-CoV-2 and spike mRNA COVID-19 vaccines.vaccines trigger different T-cell responses.
“Inactivated SARS-CoV-2 vaccines were used extensively in Asia, but are often considered inferior due to their induction of a lower antibody response compared to other types of vaccines,” said Dr. Anthony Tanoto Tan, senior co-author of the study. “This means that they might not have been as good at preventing infection, but several studies have shown that they are highly capable of thwarting the development of severe COVID-19.
“This combination of membrane, nucleoprotein, and spike-specific T-cell response is quantitatively comparable to the sole spike T-cell response induced by the mRNA vaccine. It also effectively tolerates the mutations characterizing the Omicron lineage,” said Ms. Joey Lim Ming Er, first author of the study and a second-year student PhD with the Integrated Biology and Medicine PhD track at Duke-NUS.
Senior author of the study Professor Antonio Bertoletti from Duke-NUS’ EID Program said: “The Omicron variant can effectively evade antibody neutralization, moving the evaluation of vaccination efficacy away from preventing infection and towards ameliorating disease. T cells are likely to play a more important role in this compared to antibodies, due to their ability to target virus-infected cells.
México Últimas Noticias, México Titulares
Similar News:También puedes leer noticias similares a ésta que hemos recopilado de otras fuentes de noticias.
Opinion | Meet the Post-Covid China, Same as the Pre-Covid ChinaFrom WSJopinion: When zero-Covid finally ends and travel and business resume, will the world remember the pandemic’s lesson about the Chinese Communist Party, asks Anastasia Lin
Leer más »
MIT scientists say humidity 'sweet spot' may help reduce spread of COVID-19In the study published on Nov. 16, 2022, in the Journal of the Royal Society Interface, researchers report that maintaining an indoor relative humidity between 40 and 60 percent attributed to lower rates of COVID-19 infections and deaths.
Leer más »
Scientists Reveal How Much Exercise You Need to 'Offset' a Day of SittingWe know that spending lots of time sitting down isn't good for us, but just how much exercise is needed to counteract the negative health effects of sitting down all day? Research suggests about 30-40 minutes per day of building up a sweat should do...
Leer más »
Scientists reveal the insanely perfect trick to trap lightScientists have designed a setup using which light can be trapped and absorbed by even the thinnest absorbing mediums.
Leer más »
EURUSD bears move in at key resistance, 1.0270 is keyEURUSD is battling back, down some 0.5% still, however, having fallen from a high of 1.0406 to a low of 1.0305. US Treasury yields increased on Thursd
Leer más »
Colorado’s RSV, COVID and flu hospitalizations all rising, adding new strain to health care systemMore Coloradans are hospitalized for COVID-19, flu and respiratory syncytial virus, or RSV, than were a week ago, putting the state in a potentially precarious position heading into a major holiday…
Leer más »