A proof-of-concept study showed some promising signs for the potential of using CAR T therapy to manage autoimmune disease.
in a statement that after multiple doses, the therapy restored his ability to work and travel. “Recently, I went on vacation with my lovely wife and was able to go on a 10-mile bike ride,” he says. “I’m now in full remission and feel like I gained 15 years of my life back.”
These cytokines create an inflammatory response to infection or cancer that, if prolonged, can damage healthy cells as well. CAR T cell therapy is also associated with substantial neurological complications. The current study used RNA instead of DNA to genetically engineer the cells to last for a finite life period. T cells engineered with DNA can instead live much longer, creating the negative effects.
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