Even if you had an allergic reaction to the first dose of the Pfizer or Moderna vaccines, it's safe to get the second dose, a new study finds.
Out of 189 people with initial allergic reactions, investigators looked at 159 or 84% who completed a two-dose regimen. All patients in this group, including 19 individuals with first-dose, tolerated the second dose, Blumenthal, lead author Matthew Krantz, MD, and colleagues reported.
"However, it is true that anaphylaxis with dose two would be possible even though we did not observe it in our study," she said. "While the study is compelling, the numbers are small and there is uncertainty regarding true allergic risk in patients who had anaphylaxis with the first dose of mRNA vaccine. Nineteen of 32 patients with anaphylaxis safely received a second dose, but it is not known what would have happened with the remaining 13 patients," Niraj Patel, MD, says.
"This study confirms that the vaccine is safe for re-administration, under the supervision of an allergist, in cases where there was a suspected first dose reaction," Matthew Greenhawt, MD, allergist and immunologist and director of the Food Challenge and Research Unit at Children’s Hospital Colorado in Aurora, said in an email.evaluating risk of allergic reactions to COVID-19 vaccines.
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